A Bacteroides tetracycline resistance gene represents a new class of ribosome protection tetracycline resistance
نویسندگان
چکیده
منابع مشابه
Tetracycline resistance mediated by ribosomal protection.
Resistance to tetracycline may be mediated by one of three different mechanisms: (i) an energy-dependent efflux of tetracycline brought about by an integral membrane protein (20); (ii) ribosomal protection by a soluble protein (5, 23), or (iii) enzymatic inactivation of tetracycline (33), which occurs rarely. This minireview concentrates exclusively on the second mechanism of tetracycline resis...
متن کاملDoes a tetracycline resistance determinant of class N exist?
pMV120 was reported to carry the tetracycline resistance (Tcr) determinant of class N. We obtained tetracycline-susceptible transconjugants harboring plasmids with restriction enzyme profiles indistinguishable from those of pMV120 isolated from tetracycline-resistant clones. We conclude that pMV120 is a cryptic plasmid and that class N of Tcr determinants does not exist.
متن کاملHoneybees and Tetracycline Resistance
Like animals and people, insects can serve as both collectors and disseminators of antibiotic resistance genes, as exquisitely demonstrated by a recent study (B. Tian, N. H. Fadhil, J. E. Powell, W. K. Kwong, and N. A. Moran, mBio 3[6]:e00377-12, doi:10.1128/mBio.00377-12, 2012). Notably, the relatively confined ecosystem of the honeybee gut demonstrates a large propensity for harboring a diver...
متن کاملTetracycline Resistance Gene in Asian Aquatic Environments
Antibiotic pollution has recently been a global environmental and human health concern. When bacteria are exposed to antibiotics, they express drug resistance. Drug resistance genes can be vertically and horizontally transferred in the environment. In this paper, I provide a summary of our work on one category of tetracycline resistance gene, termed ribosomal protection protein gene. In particu...
متن کاملNomenclature for new tetracycline resistance determinants.
Letters of the English alphabet have heretofore been used to name tetracycline resistance determinants. Since all 26 letters have now been used, a nomenclature employing numerals is recommended for future determinants, and one laboratory has offered to coordinate the assignment of numerals.
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1992
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.36.5.1005